Clinics may express their results in different ways and this can be confusing.We present our results in the format recommended by the HFEA, this enables you to see the number of cycles started and those cancelled at each stage.As these are the most recent figures they are expressed in clinical pregnancy rates, as these pregnancies have not yet resulted in a live birth.A clinical pregnancy is one in which a foetal heartbeat has been detected.

Multiple Pregnancies

The complications of a multiple pregnancy are significantly increased.There is a greater risk of miscarriage, raised blood pressure and diabetes. The majority of IVF twins and triplets are delivered by Caesarean section.The major antenatal complication in a multiple pregnancy is premature labour. Gross prematurity can sadly result in learning and development difficulties and even conditions such as cerebral palsy.

The stillbirth and neonatal death rate (deaths in the first 28 days after birth) for triplet pregnancy with one or more of the babies dying is 59.6 per 1000 birth events (6.0%) compared to 9.9 per 1000 (1.0%) for a pregnancy with a single baby (HFEA 9th Annual Report 2000).

There are then the potential problems of looking after more than one baby at home.

All women under 40 years of age are only allowed by law to have a maximum of two embryos transferred.

At the Leicester Fertility Centre in the last three years we have only carried out three, three-embryo transfers, all in women over 40.

Our multiple live birth rate for 2004 was 19% and we had no triplet births.

In Vitro Fertilisation

IVF treatments and results for the twelve-month period ending: 31/12/06(Note that data more recent than that given in the latest edition of the Patients' Guide is unverified)

Clinical pregnancy rates	Below 38	All ages	Patients treated	290
Treatment cycles started	24.8%	23.0%	Singleton births	62
(IVF & ICSI)	(67/270)	(79/343)	Twin births	13
Egg collection	26.4%	29.2%	Triplet births	0
	(67/253)	(79/270)	Cycles with two embryos transferred	299
Embryo transfer	27.6%	32.1%	Cycles with one embryo transferred	29
	(67/242)	(79/246)	Cycles with three embryos transferred	1
IVF only	30.1%	29.7%	Abandoned treatment cycles	95
(per embryo transfer)	(32/106)	(41/138)	Treatment with donated eggs or embryos
ICSI only	28.4%	35.1%	Cycles with donated eggs	7
(per embryo transfer)	(25/88)	(28/108)	Cycles with donated embryos	7
Frozen embryo transfers	22.0%	22.3%	Number of live births	6
(per embryo transfer)	(13/59)	(19/85)

Other results for all IVF/ICSI/FET treatments

Patients treated	271
Singleton births/ongoing pregnancies	103
Twin births/ongoing pregnancies	29
Triplet births/ongoing pregnancies	1
Cycles with two embryos transferred	227
Cycles with one embryo transferred	29
Cycles with three embryos transferred	2
Abandoned treatment cycles	87

Treatment with donated eggs or embryos

Cycles with donated eggs	4
Cycles with donated embryos	8
Number of live births/ongoing pregnancies	2

Donor Insemination

DI treatments and results for the twelve-month period ending: 31/12/05(Note that data more recent than that given in the latest edition of the Patients' Guide is unverified)

Clinical pregnancy rates	below 38	all ages	Results for DI treatments
			Patients treated	43
Treatment cycles started	8.3%	8.7%	Stimulated treatment cycles	99
	(10/120)	(11/126)	Singleton births - ongoing	10
			Twin births - ongoing	1
			Triplet births - ongoing	0

Gamete Intra Fallopian Transfer (donor gametes only)

Number of GIFT treatment cycles

0

HFEA data for 2007

++ Percentages are not calculated where there are fewer than 25 cycles or live births in each age category.

** No treatment carried out during the reporting period for age category/treatment type.

Clinical pregnancy rates for IVF & ICSI cycles using own eggs (01/01/2007 - 30/06/2007)Percentage of ICSI (41%) vs IVF (59%)

		Below 35 yrs	35 - 37 yrs	38 - 39 yrs	40 - 42 yrs	43 - 44 yrs	Over 44 yrs	Unknown age
Fresh	Per cycle started	28.2% (20/71)	16.7% (6/36)	18.5% (5/27)	++ (2/13)	++ (0/1)	**	**
	Per egg collection	37.7% (25/53)	24.0%	++ (5/20)	++ (2/11)	++ (0/1)	**	**
Frozen	Per cycle started	++ (4/24)	++ (3/10)	++ (0/6)	++ (0/3)	++ (0/1)	**	**

Donor Insemination (01/01/2007 - 30/06/2007)

	Below 35 yrs	35 - 39 yrs	40 - 42 yrs	43 - 44 yrs	Over 44 yrs	Unknown age
Treatment cycles	++ (4/19)	++ (3/21)	++ (0/7)	++ (0/2)	**	**

Treatments using donated eggs (01/01/2007 - 30/06/2007)

	Fresh embryos	Frozen embyos
Transfers	++ (2/4)	++ (0/5)

HFEA validated Data for 2005

Live birth rates for IVF & ICSI embryo transfers using own eggs (01/01/2005 - 31/12/2005)Percentage of ICSI (28%) vs IVF (72%)

		Below 35 yrs	35 - 37 yrs	38 - 39 yrs	40 - 42 yrs	43 - 44 yrs	Over 44 yrs	Unknown age
Fresh	Per cycle started	24.1% (34/141)	13.6% (9/66)	++ (8/38)	++ (2/19)	++ (0/2)	**	**
	Per egg collection	29.3% (34/116)	16.7% (9/54)	++ (8/28)	++ (2/14)	++ (0/2)	**	**
	Per embryo transfer	32.7% (34/104)	++ (9/49)	++ (8/26)	++ (2/11)	++ (0/1)	**	**
	Implantation rate	24.8% (50/202)	13.7% (13/95)	24.0% (12/50)	++ (3/23)	++ (0/2)	**	**
	Singleton live birth	16.3% (23/141)	12.1% (8/66)	++ (6/38)	++ (1/19)	**	**	**
	Twin live birth	7.1% (10/141)	1.5% (1/66)	++ (2/38)	++ (1/19)	**	**	**
	Triplet live birth	0.7% (1/141)	**	**	**	**	**	**
Frozen	Per cycle started	++ (10/38)	++ (2/11)	++ (0/17)	++ (0/8)	++ (0/1)	++ (0/1)	**
	Per embryo transfer	++ (10/33)	++ (2/11)	++ (0/17)	++ (0/8)	++ (0/1)	++ (0/1)	**
	Implantation rate	21.7% (13/60)	++ (2/11)	++ (0/14)	++ (0/7)	**	++ (0/1)	**
	Singleton live birth	++ (9/38)	++ (2/11)	**	**	**	**	**
	Twin live birth	++ (1/38)	**	**	**	**	**	**
	Triplet live birth	**	**	**	**	**	**	**

Donor Insemination (01/01/2005 - 31/12/2005)

	Below 35 yrs	35 - 39 yrs	40 - 42 yrs	43 - 44 yrs	Over 44 yrs	Unknown age
Treatment cycles	12.5% (9/72)	++ (4/23)	++ (1/11)	++ (0/5)	**	**
Singleton live birth	11.1% (8/72)	++ (4/23)	++ (1/11)	**	**	**
Twin live birth	1.4% (1/72)	**	**	**	**	**
Tripet live birth	**	**	**	**	**	**

Treatment using donated eggs

	Fresh embryos	Frozen embryos
Transfers	++ (1/3)	++ (1/12)
Implantation rate	++ (1/6)	++ (3/23)